BDBM50421578 CHEMBL13789

SMILES C(Oc1ccccc1-c1ccccc1)C1=NCCN1

InChI Key InChIKey=BPRZPBVOIULUSI-UHFFFAOYSA-N

Data  4 KI  6 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421578   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421578(CHEMBL13789)
Affinity DataIC50:  66nMAssay Description:In vitro binding affinity against cloned human alpha-1A-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421578(CHEMBL13789)
Affinity DataIC50:  28nMAssay Description:Binding affinity of compound towards Alpha-1A adrenergic receptor using membranes prepared from Rat-1 fibroblasts expressing human Alpha-1A adrenergi...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421578(CHEMBL13789)
Affinity DataEC50:  3.20nMAssay Description:Activation of human alpha-1A adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421578(CHEMBL13789)
Affinity DataEC50:  3.20nMAssay Description:Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed